NAD, short for Nicotinamide Adenine Dinucleotide, has grown in popularity over the last few years. But is NAD for anti aging truly effective?

Research from Harvard University has discovered that as we age, our levels of NAD decline, which can affect our health and longevity. It can also affect other mechanisms that our body relies on for optimal health including a class of enzymes called Sirtuins.

Sirtuins play a vital role in the regulation of inflammation and DNA protection, which ultimately age the body. NAD+ can turn off and on the Sirtuin genes that are linked to pathologies of age-related disease.

The role of NAD covers our cell proliferation, making it one of the most potent anti-ageing molecules due to its ability to decrease the rate at which your telomeres shorten. Research on telomeres is extensive, showing their length plays a significant role in the rate of aging cells.

Energy production of the mitochondria (where ATP is produced) depends on NADH being recycled back to the active NAD+.

If this recycling process is not efficient and NADH accumulates, the cells cannot produce the energy needed and will die. Health and energy production are directly correlated.

If the mitochondrion of the cell is not functioning correctly you experience lack of energy reserves in the cell, if untreated this ultimately leads to disease.

Administering a high dose NAD+ straight to the bloodstream aids in a faster more effective outcome. The high dose optimises your NAD levels, which revs up the energy engine in your cells.

What is the Difference Between NAD, NAD+, and NADH?

NAD is a coenzyme found in all living cells. It plays a key role in energy production and DNA repair.

It restores energy, improves athletic performance, aids mental clarity, helps cure cravings and could even aid in alleviating depressive episodes.

NAD, NAD+, and NADH are closely related molecules that play a vital role in cellular energy, metabolism, and anti-aging processes — but understanding their differences is key to unlocking the full benefits of NAD therapy.

The term “NAD” is often used as a general umbrella term when referring to both its active forms: NAD+ and NADH.

NAD+ (the oxidised form) is crucial for initiating chemical reactions in the body. It helps convert nutrients into energy, supports DNA repair, and promotes cellular regeneration. In anti-aging treatments, NAD+ is the primary form used to help restore youthful cellular function.

NADH (the reduced form) is created when NAD+ gains electrons during metabolic processes. It plays a key role in generating ATP, the energy currency of the cell, and supports brain function and mental clarity.

While traditional anti-aging approaches often focus on surface-level changes like creams or cosmetic procedures, NAD therapy works on a deeper level — targeting cellular decline and supporting mitochondrial health. By replenishing NAD+ levels, this therapy may improve energy, enhance cognitive performance, support mood balance, and promote overall cellular rejuvenation.

In summary, NAD refers to the broader molecule family, while NAD+ and NADH describe specific functional states of the molecule that influence how your body ages and heals at the cellular level.

What influences our own NAD+ levels?

Several factors can deplete NAD levels. Aging is the primary factor, but lifestyle choices also play a significant role. Stress, poor diet, lack of exercise, and excessive alcohol consumption can all reduce NAD levels.

To maintain or boost NAD levels, consider these lifestyle changes:

• Healthy Diet: Eat foods rich in NAD precursors, such as vitamin B3 (niacin) found in fish, chicken, and whole grains.
• Exercise Regularly: Physical activity has been shown to increase NAD levels. Aim for a mix of aerobic and resistance training.
• Reduce Stress: Practice stress-management techniques like meditation, yoga, or deep breathing exercises.
• Moderate Alcohol Consumption: Limit alcohol intake as it can deplete NAD levels.

5+ Benefits of NAD for Anti Aging

1. Boosts Energy Levels

NAD enhances cellular energy production by supporting mitochondria, the powerhouse of cells. This boost in energy can help you feel more vibrant and active. Studies and anecdotal evidence suggest increased stamina and reduced fatigue.

2. Improves Cognitive Function

NAD plays a critical role in brain health. It helps improve memory, mental clarity, and overall cognitive function. Users often report better focus and sharper thinking after boosting their NAD levels.

3. Supports Skin Health

NAD impacts skin health by improving elasticity and reducing signs of aging. Users notice smoother, more youthful skin. This benefit is due to NAD’s role in repairing DNA and supporting cellular health.

4. Enhances Metabolism

NAD aids in metabolic processes, helping with weight management and energy production. By supporting a healthy metabolism, NAD can help you maintain a healthy weight and feel more energetic.

5. Promotes Healthy Aging

Overall, NAD plays a crucial role in supporting healthy aging by preserving cellular health and optimising cellular function. It helps safeguard the body against age-related decline, potentially contributing to an increased lifespan. The long-term advantages of NAD supplementation or therapy include enhanced vitality, improved overall well-being, and the promotion of longevity.

Who would benefit from a consultation?

NAD+ consultations with our Doctors and Nurses are ideal for anyone looking to improve energy levels, focus, memory, mental clarity, and mood. They’re also beneficial for those interested in supporting healthy aging and overall cellular health for long-term wellbeing.

• Younger Adults: Can use NAD+ for prevention and maintenance of good health.
• Middle-aged Adults: May see benefits in fighting early signs of aging, improving mental performance and boosting overall vitality during busy and demanding life stages.
• Older Adults: Often experience increased energy, better cognitive function, and overall improvements in longevity and quality of life by restoring depleted NAD+ levels.

Sources:

Reiten, O., Wilvang, M., Mitchell, S., Hu, Z., & Fang, E. (2021). Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing. Mechanisms Of Ageing And Development, 199, 111567. doi: 10.1016/j.mad.2021.111567

Fouquerel, E., & Sobol, R. (2014). ARTD1 (PARP1) activation and NAD+ in DNA repair and cell death. DNA Repair, 23, 27-32. doi: 10.1016/j.dnarep.2014.09.004